Har du forsøkt raloxifene? Enkelte studier viser svært gode resultater for å reversere gynekomasti, selv flere år etter den først oppstod. Nolvadex kan også gjøre dette, men har lavere sannsylighet for å fungere godt ved "gammel" gynekomasti enn raloxifene.
"Raloxifene is a second-generation selective estrogen receptor modulators (SERM). In 34 healthy males at the dose of 60 mg/day for one month it increased serum testosterone by 20%, and slightly decreased serum estradiol. When used in eugonadal patients with gynecomastia, 75% had a reduction in the size of breast tissue of at least 50% (average, 73%) in the first two months of treatment. However, the study was small and the males have wide range of ages (42).
In thirty eight patients with persistent pubertal gynecomastia who received reassurance alone or a 3- to 9-month course of an estrogen receptor modifier (tamoxifen or raloxifene) there was a mean reduction in breast nodule diameter by 2.1 cm after treatment with tamoxifen and 2.5 cm with raloxifene. Some improvement was seen in 86% of patients receiving tamoxifen and in 91% receiving raloxifene, but a greater proportion had a significant decrease (>50%) with raloxifene (86%) than tamoxifen (41%). No side effects were seen in any patients. Authors suggested that raloxifene may be safe and effective in reducing persistent pubertal gynecomastia, with a better response compared to tamoxifen (43)."
Sitat:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166145/
Sist endret av En deling; 4. oktober 2021 kl. 19:29.